I3C SAP 60 caps by Nutritional Fundamentals for Health

I3C SAP 60 caps by Nutritional Fundamentals for Health

Nutritional Fundamentals for Health


$ 31.60
$ 31.60

Pre-order may require a few extra days for processing

Indole-3-carbinol (I3C) is a phytochemical derived in high concentrations from the Brassica family of vegetables, including broccoli, cauliflower, Brussels sprouts, and cabbage. I3C and its derivative compounds have been shown to exert anticancer mechanisms in the human body. I3C has been shown to exhibit direct antiestrogenic activity via competitive inhibition of estrogen receptors; upregulate the cytochrome P450 isoenzymes CYP1A1, CYP1A2, and CYP1B1, thereby increasing estrogen metabolism; shift estrogen metabolism away from the more proliferative (16‑OHE1) towards the more protective (2‑OHE1) estrogen species; induce cancer cell apoptosis via NF‑κB pathways; inhibit cancer cell growth at the G1 stage; and increase the expression of p21, p27 and p53 tumor suppressors. The use of I3C for the prevention and treatment of breast, endometrial, colon, and prostate cancers as well as for the treatment of herpes simplex virus (HSV) and human papillomavirus (HPV), including cervical dysplasia and cervical cancer, has been studied in depth in both animals and humans with favourable results.

Do not use if seal is broken. 
Keep out of reach of children.

Cautions and warnings: For adult use only. Consult a health-care practitioner prior to use if you are taking any medication; if you are attempting to conceive; if you have a liver disorder or develop liver related symptoms (e.g. abdominal pain, jaundice, dark urine); if you have or are pre-disposed to cancer. Discontinue use if you experience joint pain or hot flashes. Do not use if you are pregnant or breastfeeding.

Contraindications: Consult a health-care practitioner prior to use if using anti-estrogenic drugs.

Known adverse reactions: Hypersensitivity is known to occur; in which case, discontinue use. Discontinue use and consult a health-care practitioner if you develop a rash or gastrointestinal upset.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Serving Size: 1 Capsule Amount Per Serving Indole-3-carbinol ... 150mg Other Ingredients: Vegetable magnesium stearate, microcrystalline cellulose, and a non‐GMO vegetable capsule composed of vegetable hypromellose and purified water. Does not contain gluten, wheat, corn, dairy, sugar, starch, yeast, preservatives, artificial flavor or color.

Returns Policy

You may return most new, unopened items within 30 days of delivery for a full refund. We'll also pay the return shipping costs if the return is a result of our error (you received an incorrect or defective item, etc.).

You should expect to receive your refund within four weeks of giving your package to the return shipper, however, in many cases you will receive a refund more quickly. This time period includes the transit time for us to receive your return from the shipper (5 to 10 business days), the time it takes us to process your return once we receive it (3 to 5 business days), and the time it takes your bank to process our refund request (5 to 10 business days).

If you need to return an item, simply login to your account, view the order using the 'Complete Orders' link under the My Account menu and click the Return Item(s) button. We'll notify you via e-mail of your refund once we've received and processed the returned item.


We can ship to virtually any address in the world. Note that there are restrictions on some products, and some products cannot be shipped to international destinations.

When you place an order, we will estimate shipping and delivery dates for you based on the availability of your items and the shipping options you choose. Depending on the shipping provider you choose, shipping date estimates may appear on the shipping quotes page.

Please also note that the shipping rates for many items we sell are weight-based. The weight of any such item can be found on its detail page. To reflect the policies of the shipping companies we use, all weights will be rounded up to the next full pound.


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